T-Coffee A collection of tools for Computing, Evaluating and Manipulating Multiple Alignments of DNA, RNA, Protein Sequences and Structures

Alignment

T-Coffee Aligns DNA, RNA or Proteins using the default T-Coffee   >>  Cite
M-Coffee Aligns DNA, RNA or Proteins by combining the output of popular aligners   >>  Cite
R-Coffee Aligns RNA sequences using predicted secondary structures   >>  Cite
Expresso Aligns protein sequences using structural information   >>  Cite
PSI-Coffee Aligns distantly related proteins using homology extension (slow and accurate)   >>  Cite
TM-Coffee Aligns transmembrane proteins using homology extension
Pro-Coffee Aligns homologous promoter regions   >>  Cite
Accurate Automatically combine the most accurate modes for DNA, RNA and Proteins (experimental!)
Combine Combines two (or more) multiple sequence alignments into a single one   >>  Cite

Evaluation

Core Evaluates your Alignment and outputs a Colored version indicating the local reliability.   >>  Cite
iRMSD-APDB Evaluates Multiple Sequence Alignment using structural information with APDB and iRMSD.   >>  Cite

Other

Advanced Run your alignment using full featured T-Coffee options.   >>  Cite

Highlight

RECOMB is a well-established scientific conference bridging the computational, mathematical, and biological sciences. The conference features keynote talks by preeminent scientists in the life sciences, together with presentations of refereed research papers in computational biology.

RECOMB 2012 will take place in vibrant and beautiful Barcelona from 21 to 24 April 2012. There will be a strong focus on the computational challenges arising from the extraordinary developments in high throughput technologies.

For more information visit http://recomb2012.crg.cat

Useful links

Google Group Support and discussion group
tcoffee.org Find out more about T-Coffee project and documentation
Cedric Notredame Home page, Courses and Blog
Download Sources and binaries are available for download at this link
Twitter Check it out for latest T-Coffee developments and new tips
Facebook T-Coffee has a page on Facebook

Mirror sites

Bioinfo for dummies
The Book Bioinformatics For Dummies contains a T-Coffee tutorial and many other online resources.
Vital-IT Vital-IT, Swiss Institute of Bioinformatics (SIB)
EBI EBI, European Bioinformatics Institute
IGS CNRS  IGS lab., CNRS
>Max-Planck Institute Max-Planck Institute for Developmental Biology
Cornell Cornell
EMBNet-Spain EMBNet-Spain